Psychological Aspects Of Type 1 Diabetes In Adults

When considered from an experiential perspective, type 1 diabetes (Type 1 diabetes mellitus) represents a significant stressor for individuals and their families. A comprehensive understanding of psychological factors related to Type 1 diabetes mellitus requires investigation of (/) the impact of Type 1 diabetes mellitus upon psychological adjustment and (ii) the impact of psychological adjustment upon medical outcomes for diabetes mellitus 1. Both of these directions of influence are reviewed below regarding each of the most prevalent and/or problematic psychological adjustment problems for adults with Type 1 diabetes mellitus. When comparing with other chronic health conditions, from an experiential perspective, it is important to consider: •   disease factors, including … Continue reading

Insulin Therapy In Adults With Type 1 Diabetes Mellitus

Insulin is the cornerstone of pharmacotherapy for the estimated 0.73 to 1.46 million persons with type 1 diabetes mellitus in the United States. While the peak incidence … Continue reading

Physiologic Replacement Therapy Insulin Regimens

Conventional Insulin Therapy Conventional insulin therapy is used to describe simpler, usually fixed dose insulin regimens, such as single daily injections, or two injections per day of regular and NPH insulin, either mixed together in the same syringe or provided as a premix of insulins, which are given in prespecified doses before breakfast and dinner. Such regimens are based on the concept that each of the insulin components in the two doses is covering insulin needs for … Continue reading

Planning for Sick Days, Surgery, and Travel

Diabetes control can be adversely affected by stressful situations related to physical or emotional distress. Health care providers must be able to advise patients with diabetes who become ill with infections, injuries, or other ailments that complicate their diabetes management routine and cause hyperglycemia. Definition of a sick day: A sick day could be caused by a variety of situations, from a common cold to a broken bone to a death in the family. If the patient is thrown off of his/her usual diabetes … Continue reading

Patient guide to sick day management

Type 1 Diabetes What is a sick day? Any day that you are not feeling well, having trouble eating your usual meals, or are experiencing a medical procedure or extreme emotional upset. Why are sick days important? Diabetes is affected not only by what you eat and the insulin you take, but also by other hormones in the body. Hormones that work against insulin usually increase during illness or stress, causing the insulin you take to work less effectively. This is why illness and stress cause the blood sugar to rise. Diabetic ketoacidosis is a severe, life-threatening complication of diabetes that commonly occurs during illness or severe stress. This develops due … Continue reading

Insulin and insulin analogs

Insulin is frequently initiated when maximum dose of single or combined oral agents fail to control glucose levels. Diabetes is a progressive disease with continuing loss of β-cell function — patients should be informed that this is the natural history and they have not personally failed. Insulin and insulin analogs are available in a number of long-, intermediate-, and short-acting preparations and in an inhaled form, recently approved by the FDA for use in patients with type 1 or type 2 diabetes. When initiating the older patient on insulin, the advantages and concerns of treatment need to be reviewed. Aspects such as physical, mental, and visual problems must be carefully assessed; … Continue reading

Action Times

People may respond to preparations of insulin and insulin mixtures differently, so it is important to find the types of insulin that work best for you. Each type of insulin has a different action time, a term that describes the length of time it takes to begin acting and how long its effect lasts. The action times of insulin are due to the following three features: ■ onset: the length of time it takes for insulin to reach the blood and begin lowering blood glucose levels ■ peak time: the time during which insulin is at its maximal strength in lowering blood glucose levels ■ duration: the length of time in … Continue reading

Premixed Insulin

You might be advised to take a mixture of regular or rapid-acting and NPH insulin in one injection. You can mix them yourself. Or you may be able to buy the insulin already mixed. Mixtures of regular and NPH insulins come in various combinations that make them more convenient and easier to handle. For example, you can buy a 50/50 mixture of NPH and regular insulin, or you can buy a mixture that contains 30 percent regular insulin and Rapid- or short-acting insulins can both be used for bolus doses of insulins. But many people find rapid-acting insulins more convenient. Rapid-acting insulins can be used by people with either type 1 … Continue reading

Buying and Storing Insulin

Don’t assume that most pharmacies will charge the same price for insulin. The same insulin at one pharmacy or outlet may be several dollars cheaper than that found somewhere else, so it pays to shop around. You might receive a discount for buying certain quantities at your pharmacy or by ordering through the mail. Be sure to ask your pharmacists whether they offer discounts for large orders. Your insurance company or managed care provider may have an agreement with “preferred pharmacies” to offer insulin at reduced rates. Check with your insurance company or managed care provider to see whether it offers this service. By using these services you may be able … Continue reading

Insulin: Uses. Preparations

Uses and Administration Insulin is a hormone that plays a key role in regulating carbohydrate, protein, and fat metabolism. The main stimulus for its secretion is glucose, although many other factors including amino acids, catecholamines, glucagon, and somatostatin, are involved in its regulation. The secretion of insulin is not constant and peaks occur in response to the intake of food. The major effects of insulin on carbohydrate homoeostasis follow its binding to specific cell-surface receptors on insulin-sensitive tissues, notably the liver, muscles, and adipose tissue. It inhibits hepatic glucose production and enhances peripheral glucose disposal thereby reducing blood-glucose concentration. It also inhibits lipolysis thereby preventing the formation of … Continue reading